Dear Kris,Here's a summary that might be useful...
The Technical Significance
Vitalethine is a natural product...
http://www.vitaletherapeutics.org/nomncltr.htm
http://www.vitaletherapeutics.org/vtlms4vm.htm
http://www.vitaletherapeutics.org/vtlvamas.htm
...that is probably destroyed by chemical warfare agents along with the enzymic receptor for the vitaletheine modulators:
http://www.VitaleTherapeutics.org/vtlwargs.htm
Vitalethine dramatically stimulates immunity, even in an AIDS model at the University of Arizona at Tucson, and in a manner reported to prevent diabetes and presumably other autoimmune reactions. Thus, it has potential in preventing and treating infectious, immunosuppressed, and autoimmune disease and as a defense against chemical and biological warfare attacks. In addition, beta-alethine, probably containing traces of vitalethine, was found to be a radioprotector by the Armed Forces Radiobiological Research facility. Our work in identifying and ranking environmental problems also suggests that the tons of plutonium, now missing, is our most potent toxic concern, and that remedial solutions should be worked out to counter the threat of a dirty plutonium bomb that could make large portions of our globe uninhabitable for tens of thousands of years:
http://www.vitaletherapeutics.org/vtlrefab.htm
Inexpensive solutions appear to be at hand for remedial programs for this and other threats, as well as for removing plutonium from DOD and DOE workers who were inadvertently exposed, and for safely trapping and disposing of plutonium-contaminated wastes.
For example, a more effective and stable prodrug form of vitalethine, specifically denied and precluded from UNM's portfolio by litigation, is being synthesized on a regular bases for experimental use in cancer research, since it predictably elicits a therapeutic response against a variety of tumors in a variety of mammalian species, including veterinarian models. Significantly, this compound is 100% effective in producing therapeutic responses in horses with melanoma. At the same time, this biologically active form theoretically is not directly poisoned by plutonium. This natural "prodrug" complex also is more stable and is already activated (sic., armed) to the sulfenic acid form, thought to be the actual biologically active form of vitalethine. This sulfenic acid form can easily be freed from vitalethine's disulfide through the hydrolysis (disproportionation) into thiol and sulfenic acid forms. As such, this already armed "trojan horse" delivery system bypasses the nutritional, toxicological, and enzymic problems of naturally-occuring and synthetic vitalethine. Both the thiol and sulfenic acid forms are poisoned by known carcinogens and immune suppressants, including chemical and biological warfare agents, such poisons probably precipitating the cancer and other health problems we identify as "dis"ease.
This prodrug compound has been made available for more than a decade for veterinarian investigation with the sole requirement being a release from legal liability should the therapy fail to provide the predicted results for any reason that is now unforeseen. Suffice it to say that there has never been a claim in this regard. We have tentatively established that ethoxyquin in the diet, a preservative found in pet food and some spices used for human consumption, may contribute to the relatively rare failures of this therapeutic approach. Melatonin is probably essential for the induction of the enzymic receptor for vitalethine, and ethoxyquin (being a structural analogue of the indole, melatonin) can interfere with melatonin and shut down vitalethine's therapeutic pathway. Thus, melatonin for better sleep under stressful conditions can have a very positive effect upon overall and immune health:
http://www.vitaletherapeutics.org/vtlmoflo.htm
Currently, we are getting supplies together to dilute another large batch of compound to appropriate therapeutic concentrations for the species of mammals being studied. It is crudely estimated that about 300 effective human treatments could be prepared for about one penny.
The Fraud
UNM sued the inventors for more than six years to suppress accurate information about the vitaletheine modulators, going so far as to commit patent fraud with its licensee by underwriting others' false claims to inventorships while also surreptitiously corrupting structures and biological activities in what were once legitimate patents and applications by the true inventors. This deliberate and blatant fraud is now documented and will be reported as required by patent law. For example, the spontaneous activation of the benzyl derivative within mammalian cells was corrupted by UNM, its licensee, and/or the patent office in later patents and applications bearing the true inventors' names. They falsely substituted nitrogens for hydrogens to corrupt the structure of the best therapeutic candidate and its spontaneous biological release within the cell, corrupting even water in the process as N2O:
http://www.vitaletherapeutics.org/vtlbzact.htm
To our knowledge, UNM and its licensee are making the wrong compounds or grossly contaminated preparations of the compounds, and are NOT a reliable source for the authentic compounds, and they have demonstrated that they are not a reliable souce of information about the authentic compounds. For example, the admitted substitution of acetone for acetonitrile by UNM's licensee predictably caused the production of a Schiff's base of beta-alethine and acetone, instead of ultimately vitalethine. This Schiff's base is frighteningly close, structurally, and is therefore an analogue of vitalethine that probably interferes with the biological actions of vitalethine:
http://www.vitaletherapeutics.org/vtlvamas.htm
One cancer patient, in a laughable clinical trial by UNM's licensee in just two human subjects, was apparently injected with a contaminated or artifactual preparation and had the tumor grow explosively, instead of going away, indicating that the corrupted preparation had the exact opposite effect of the uniformly beneficial TH-2 responses observed for authentic vitalethine. The other person in this so-called "clinical trial" reportedly had to quit because no benefit was derived from the contaminated or artifactual compound. I would strongly recommend that everyone be very wary of anything coming hap"hazard"ly from UNM or its licensee, and consider such materials only if they are closely aligned with the scientifically validated results produced by the true inventors.
The Solution
UNM was asked to produce discovery for any inaccurate information or conclusions on VitaleTherapeutics' website and failed to produce any that would affect conclusions drawn. One miscalculation that was identified has been corrected since trial. Thus, for admittedly accurate chemical and scientific information, assuming US 5,370,868 has not been changed since trial, one should see this particular patent, the June '04 Townsend Letter article, the November 1994 Cancer Research articles, and the Journal section of our website:
http://www.VitaleTherapeutics.org/vtlchmup.htm
All the chemical information from our non-profit organization is accurate for synthesizing the authentic compounds, both vitalethine and the sulfenate-linked benzyl carbamate (Trojan horse) dimer of the naturally-occuring, already activated substance, the sulfenic acid probably controlling cancer and heart disease as illustrated on our website:
http://www.Vitaletherapeutics.org/vtlhmgmo.htm
Feel free to ask quesitons by e-mail or by video-conferencing through Yahoo as identified on our website. Obviously, this sharing of information worldwide can have a significant impact on worldwide health and counterterrorism efforts, no matter what the ultimate legal disposition of this matter with UNM.
It is signficant that the "Conway" decision of the Federal District Court of New Mexico, depriving the true inventors of their 1st, 4th, and 7th Amendment, Constitutional rights, was entered 9/11/01.
Part Two